イワミ　ノリオ   岩見　徳雄    所属   理工学部 総合理工学科    職種   准教授
言語種別	英語
発行・発表の年月	2021/12
形態種別	学術雑誌
査読	査読あり
標題	Chronic ecotoxicology and statistical investigation of ciprofloxacin and ofloxacin to Daphnia magna under extendedly long-term exposure
執筆形態	共著
掲載誌名	Environmental Pollution
掲載区分	国外
出版社・発行元	Elsevier
巻・号・頁	291,pp.118095
担当範囲	特定不可能
国際共著	国際共著
著者・共著者	Tan-Duc Nguyen, Tomoaki Itayama, Rameshprabu Ramaraj, Norio Iwami, Kazuya Shimizu, Thanh-Son Dao, Thanh-Luu Pham, Hideaki Maseda
概要	Ciprofloxacin (CFX) and ofloxacin (OFX) are two of the most often used fluoroquinolone antibiotics, and their residues are found in large amounts in various aquatic settings. D. magna was performed during 42 days under exposure to CFX and OFX concentrations of 50, 500, and 5000 μg L⁻¹. All exposure conditions did not cause mortality for D. magna. CFX exposure at 500 μg L⁻¹ resulted in an earlier oogenesis date and increased brood size in the second birth. The Poisson-based generalized linear mixed-effects model revealed that the reduction of fertility was statistically significant for the CFX and OFX exposures at 5000 μg L⁻¹. On the other hand, the production of dead eggs as offspring degradation was also found significantly as maternal D. magna exposed to antibiotics at 5000 μg L⁻¹. In addition, following long-term exposure to antibiotics, maternal adaptation to antibiotics was established for offspring deterioration and fertility.