イワミ ノリオ
岩見 徳雄 所属 理工学部 総合理工学科 職種 准教授 |
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言語種別 | 英語 |
発行・発表の年月 | 2023/07 |
形態種別 | 学術雑誌 |
査読 | 査読あり |
標題 | Toxicity of ciprofloxacin and ofloxacin to Moina macrocopa and investigation of p-value adjustments for (eco)toxicological studies |
執筆形態 | 共著 |
掲載誌名 | Drug and Chemical Toxicology |
掲載区分 | 国外 |
出版社・発行元 | Taylor & Francis |
担当範囲 | 特定不可能 |
国際共著 | 国際共著 |
著者・共著者 | Tan-Duc Nguyen, Tomoaki Itayama, Norio Iwami, Kazuya Shimizu, Thanh-Son Dao, Thanh Luu Pham, Vinh Quang Tran and Hideaki Maseda |
概要 | In this study, we assessed the no observed adverse effect concentration (NOAEC) of ciprofloxacin (CFX) and ofloxacin (OFX) on Moina macrocopa across a concentration range of 0–400 µg L−1. Furthermore, we investigated multiple p-value adjustments to determine the NOAECs. Our analysis yielded consistent results across seven different p-value adjustments, indicating NOAECs of 100 µg CFX L−1 for age at first reproduction and 200 µg CFX L−1 for fertility. For OFX treatment, a NOAEC of 400 µg L−1 was observed for both biomarkers. |