イワミ ノリオ
  岩見 徳雄
   所属   理工学部 総合理工学科
   職種   准教授
言語種別 英語
発行・発表の年月 2023/07
形態種別 学術雑誌
査読 査読あり
標題 Toxicity of ciprofloxacin and ofloxacin to Moina macrocopa and investigation of p-value adjustments for (eco)toxicological studies
執筆形態 共著
掲載誌名 Drug and Chemical Toxicology
掲載区分国外
出版社・発行元 Taylor & Francis
担当範囲 特定不可能
国際共著 国際共著
著者・共著者 Tan-Duc Nguyen, Tomoaki Itayama, Norio Iwami, Kazuya Shimizu, Thanh-Son Dao, Thanh Luu Pham, Vinh Quang Tran and Hideaki Maseda
概要 In this study, we assessed the no observed adverse effect concentration (NOAEC) of ciprofloxacin (CFX) and ofloxacin (OFX) on Moina macrocopa across a concentration range of 0–400 µg L−1. Furthermore, we investigated multiple p-value adjustments to determine the NOAECs. Our analysis yielded consistent results across seven different p-value adjustments, indicating NOAECs of 100 µg CFX L−1 for age at first reproduction and 200 µg CFX L−1 for fertility. For OFX treatment, a NOAEC of 400 µg L−1 was observed for both biomarkers.